The (more frequent) 250 mg dose of niacinamide is 40 to 50 % more effective in the treatment of arthritis than the (less frequent) 500 mg. dose. As an illustration, see the reprint of my Tom Spies Memorial Lecture: Niacinamide, a Most Neglected Vitamin. This illustrative case history begins on page 17 column 2 and continues on page 18 column 2.
If Dracula were an old woman, he would have sounded a lot like Mrs. Kelremor. But there was no other physical resemblance. Just shy of eighty, this middle-European immigrant lady had been a housekeeper for decades. Overweight, bent over, worn out and weighted down with cares, she came to see me primarily because of osteoarthritis.