My aunt needed oxygen to put on her socks. A severe case of emphysema, which a lifetime of smoking had failed to cure, was the reason. She was just one of an estimated 16 million Americans suffering from Chronic Obstructive Pulmonary Diseases (COPD), all primarily caused by tobacco use. The fourth leading cause of death, COPD kills over 100,000 annually. That number is increasing; medical research has contributed virtually nothing to stop it.